Dupuytren’s nodule

Dupuytren’s nodule self-treatment

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Dupuytren’s nodule is the first sign of Dupuytren’s disease.  One or more small lumps on the palm appear near the base of one or more fingers.  A Dupuytren’s nodule forms when excess collagen and fibrin collects under the skin of the palm. The surface becomes distorted and puckered by the underlying excess collagen.The Dupuytren’s nodule is the first sign of Dupuytren’s disease.  Usually, at the start of the problem, one or more small lumps on the palm appear near the base of one or more fingers. The Dupuytren’s nodule forms on the surface when excess collagen and fibrin collects under the skin of the palm. The surface becomes distorted and puckered by the underlying excess collagen.

While the tiny palm lump on the surface gets people’s attention, what happens below the surface of the skin is far more important. The excess collagen and fibrin cause the normally flexible supporting tissue of the palm to thicken, expand and tighten. This process can also create little dimples and creases, as well. The palm lump creates a thick cord as it matures. This cord attaches itself to the finger. Eventually, the cord contracts or shrinks, pulling the finger down and keeps it in a bent position. At this point, Dupuytren’s disease becomes Dupuytren’s contracture.

Most everything about the Dupuytren’s nodule is variable.  Even the size and shape of Dupuytren’s palm nodules are variable. They range in size from a dime to a quarter, although they can be smaller and larger than this.

Eliminate the Dupuytren’s nodule with safe natural treatment

Great news!  It is important for anyone with Dupuytren to understand that Dupuytren can self-heal.  The body self-heals an unknown percent of early Dupuytren disease, and even reduces later, larger palm nodules and cords of Dupuytren’s contracture.

Surgery is not always necessary to eliminate the Dupuytren’s nodule.  Since 2002 the Dupuytren Contracture Institute has helped people who struggle with an expanding and tightening lump on the palm. Those who closely follow the DCI treatment strategy early can do rather well.  We hear from 8-10 people who use our large treatment plan reporting they see moderate to marked reduction of their signs and symptoms of Dupuytren, for every one report of failure.

We find that the larger the treatment plan, and the closer a person follows DCI treatment suggestions, the better the Dupuytren self-heals. For information about DCI treatment plans.

Hand surgery is always an option. However, it makes sense to first attempt non-surgical treatment and therefore possibly avoid the inherent risks of surgery.

How do use natural therapy for Dupuytren’s disease?
► It’s easy.  Click on Start Dupuytren’s Treatment

Take the Dupuytren’s nodule seriously

There is no way to know how large or small a Dupuytren’s problem will eventually become in the early stage of Dupuytren palm nodule development.  Yes, some palm lumps develop slowly, staying small for a decade or more.  And some palm lumps grow into several fingers to make life miserable and a struggle to perform basic activities. Yet, the medical literature says that 30%-40% eventually need palm surgery. Therefore, the best strategy is to take all Dupuytren’s nodules seriously.

DCI talks to many people about their Dupuytren’s disease.  A common attitude is, “My little palm lump has been with me for a long time. It really doesn’t bother me. If it becomes a big problem later, my doctor said I can just have it cut out. So, what’s the big deal?”  The big deal is that DC hand surgery sometimes has small and large complications due to the tendency to make too much collagen when stimulated.  This causes the surgery to heal in unexpected ways with unexpected consequences, regardless of the skill or intention of the surgeon.

That is like saying, “My doctor said if the little grease fire in my kitchen gets any bigger later, I can always call the fire department to put it out.” Why would anyone take that risk? Why wouldn’t you take care of a small problem while it is small, and easier to handle?

It is silly to wait for a Dupuytren’s nodule to get worse.  Allowing the palm nodule to worsen is a lost opportunity to try to heal it naturally. That lost time only benefits the hand surgeon. For the patient, it is best to be conservative.  Take care of a small problem while it is still small and easier to self-treat.

Dupuytren’s hand surgery has unique risks

The big deal about hand surgery for Dupuytren’s contracture is important to understand. The trauma of hand surgery can act as a trigger or stimulus for even more collagen production in the hand. This is called Dupuytren recurrence when the Dupuytren nodule or cord comes back after being surgically removed.  As a result, hand surgery for DC is riskier, and has more complex reactions than having other kinds of hand surgery.  Recurrence happens because it is the nature of Dupuytren’s contracture to make too much collagen. This explains why so many people have 2-3-4 hand surgeries before they eventually refuse to have more.

What are the odds of little Dupuytren’s disease palm lumps becoming a surgical problem?   Fairly high.  Most authors say 30%-40% Dupuytren’s nodules undergo surgery. This does not necessarily have to happen, however. There is a lot a person can do to reverse or slow down Dupuytren’s disease. Do all that you can to improve your ability to self-heal or reverse the collection of excess collagen of your palm nodules.  DCI can show you how.

Major or minor hand problem

For some, Dupuytren’s disease can remain a minor inconvenience for a long time.  While for others it quickly becomes a major problem when the hand does not fully open.  Simple daily activities become difficult, or impossible, to do. Tasks that are an important part of daily life become burdensome, and eventually impossible:

  • Wash the hands and face
  • Operate a cell phone or computer
  • Use a knife and fork while eating
  • Get something out of your pocket
  • Turn a doorknob to open a door
  • Use the bathroom
  • Brush your teeth
  • Button clothing
  • Wear gloves
  • Drive a car

How much the Dupuytren’s palm nodule complicates life depends on many factors in a person’s history.  The more that are present, the stronger the likelihood of rapid and aggressive Dupuytren’s contracture occurring:

  • Members of immediate family have DC
  • DC begins early (under 50 years of age)
  • Presence of liver disease
  • History of diabetes
  • Presence of Garrod’s knuckle pads
  • Long history of manual labor

Final thoughts about the Dupuytren’s nodule

Don’t be fooled by a slow start of the Dupuytren’s nodule.  While it might seem like a minor inconvenience and curiosity, 30-40% eventually make a person’s life so complicated and frustrating that they have surgery to straighten the finger.  Only then do they learn that the Dupuytren nodule can return or recur after hand surgery.

Take advantage of the fact that that Dupuytren’s nodules self-heal.  DCI has worked since 2002 to help people do a better job of healing their Dupuytren’s nodule.  We believe it is smart to use the time your doctor says to wait for the palm lump to get worse, to help your body self-heal.

How do use natural therapy for Dupuytren’s disease?
► It’s easy.  Click on Start Dupuytren’s Treatment


Does this sound like Dupuytrens contracture to you?

I was told i have Dupuytren’s contracture but i have my doubts. Symptoms of a very very painful middle finger in my non-dominant hand. If i touched or banged it, it could bring me to my knees. After the major acute pain stopped i had burning and tingling back of hand and palm side of finger. My finger curves and i can only straighten it manually. The finger triggers if i suddenly grab for something. It hurts like hell and i have to manually snap the finger up. It does not bend down at the proximal palm joint like most pictures show. the finger is swollen. made worse by weight gain. Now my right middle finger is starting to bother me although not as painful. My thumbs trigger though getting better, my right thumb has limited range of motion, and my left ring finger triggered in past. I cannot bend my middle fingers past 90 deg from proximal or middle knuckle making it difficult to grasp, open jars etc. I manually straighten my fingers daily. Diet does seem to make a difference, i have cut out sugar and wheat, salt, restaurant food aggravates.

I work full time at a job where i use computer. my other job is as a massage therapist, (no brainer, this is a lot of hand use). I am able to compensate to do massage and typing accentuates the curve as does driving (no power steering). I think i am going to start your dietary supplements but i still doubt the DC diagnosis… sorry this is so long trying to be clear and thorough. Does it sound like Dupuytrens contracture to you?

I have on one or two occasions i have  felt tightening in my foot and my wrists and forearm tendons seem to be involved. I can see the tendon in the hand is prominent, but no nodules. The finger bones close to the palm are sore. Upon manual manipulation i can feel popping in the middle phalanx joints of the affected fingers.I was diagnosed by a neurologist as having a slight nerve problem in the left forearm between the bones…interosseous nerve syndrome? I think, it is not very common. He is very good but didn’t see this as a nerve issue.

I am of Scandinavian descent, my father did have a contracture after breaking his hand in a jackhammer accident.

ANY ides, brief or otherwise would be helpful. I live in Hawaii and it is like a rural community. Very informed. Specialists are not the norm.

If needed i will call for a paid consult and can send pictures of my hand. I’m so happy to have found this site after a year of no meaningful information.

Thank you sincerely, Aloha, Dawn Matney


Aloha to you Dawn,

Thank you for the detailed description of your problem with finger and hand pain, and for the complement. My intention with the Dupuytren’s Contracture Institute is to offer meaningful information and suggestions while under the limited circumstance of not being able to see and examine the problems for which people need help. As  you can imagine I am only able to offer an educated guess as to what is going on with your hand problem.Ultimately you have to decide what is the truth of your situation and if you feel it is appropriate to seek out another opinion for a diagnosis and treatment.

Based solely on the description you offer, your problem does not sound as much like Dupuytren’s contracture.  My impression is that it is more likely an inflammation of the palmar tendon sheaths due to the trauma of extended overuse. 

Using your hands rather continuously as you do now between full time work with a computer plus massage therapy is more than your hands can tolerate.   In that last sentence I would like for you to consider the operative phrase, “as you do now.”   What I am suggesting to you is that you evaluate exactly how you are typing on the keyboard and the way you use your arms and hands for body work. I suspect that you are using bad habits that are stressing your shoulders, arms forearms and hands, and this is the cause of most – if not all of your current hand pain.  I tend to be far too aggressive when I type; by the end of the day, if I have not controlled my hand action, I can make the tips of my fingers sore to the touch.  You too are probably not working to your best mechanical advantage.  Observe yourself while at work and see what you can do differently, or not at all, that might help your situation.              

While trigger finger and pain are sometimes a component of Dupuytren’s contracture, no the primary problem as you have presented your current situation.  Also, while you are of Scandinavian descent (and hereditary factors favor those of Scandinavian descent for Dupuytren’s contracture) you made your father’s hand problem sound more like a hand problem that arose from one particular work accident, so my impression is that you probably do not have DC in your immediate family history.  You do not report a palm nodule nor cords and these are almost mandatory to establish a diagnosis of Dupuytrens.   Lastly, you report that your diet seems to make an impact on your hand symptoms; this would not likely be true for a pure Dupuytren problem.  Put all these things together  and to me it does add up as a case of Dupuytren’s contracture.

I suggest that you look around your island to see if there is a good chiropractor or naturopath who can work with you from a dietary, structural and soft tissue basis to control and eliminate your upper extremity problem. 

Is there a substitute for DMSO I can use to treat my hand?

Hello Dr. Herazy,

I am researching the therapies you are recommending. Since I am allergic to Sulfa drugs I probably do not want to use DMSO. Assuming I can tolerate the topical E and the CP Serum is there another carrier oil or gel that I could use instead of the DMSO? Maybe Jojoba oil or olive oil?

Thank you

Diane B


Greetings Diane,

Although it is not as good as DMSO for the purpose of driving the topical E and Super CP Serum copper peptides into the Dupuytren palm nodule and cord tissue, you can use Emu oil for this purpose.    The emu is a bird from New Zealand and Australia.  Oil from this bird has some tissue penetrating properties and can be used also.   TRH

Why is Xiaflex not indicated for palmar nodules?


Why is Xiaflex not indicated for palmar nodules? If it weakens and dissolves the cord, why would it not dissolve a nodule?

Thank you,



Greetings RSW,

The fact is a Xiaflex injection would weaken and dissolve a palm nodule, but then you would have a hole in the palm of your hand.   For this reason Xiaflex is only used to treat Dupuytren cords which are below the surface of the skin.

Of course, with Xiaflex injections the medical profession knows that the Dupuytren cords will return rather quickly, usually just a few years, and more injections would then be used.  There are two problems in doing this:  1. No one knows what happens to the body with repeated Xiaflex injections.  2. Each time a person has a Xiaflex injection as a Dupuytrens treatment he or she runs the risk of having the Xiaflex dissolve normal tissue and cause problems greater than having Dupuytren’s contracture.  For this reason we strongly suggest that anyone with Dupuytrens contracture first attempts to correct their problem using Alternative Medicine.  TRH     

DMSO Questions

I the dmso you sell a “pharmaceutical” grade or “industrial” grade?

How is the dmso applied and in what amount?


The DMSO is  of a pharmaceutical grade from the oldest medical DMSO source in the U.S., still operated by Stanley Jacobs, MD, who did the original research at the Washington State School of Medicine on the medical use of DMSO in the late 1950s.   Dr. Jacobs is in his 90s and still teaches and works in the laboratory at the medical school.  We use his Dusa Sal formula that he recommends for Dupuytren contracture.

The Dusa Sal DMSO is applied to the hand directly over the palm nodule and cord formations, usually just a few drops per application.   In additional to the Dusa Sal we recommend that you also use vitamin E oil and a copper peptide at the same time.    When you get Dusa Sal from DCI you will receive a detailed instructional sheet of information in your order so that you know exactly how to apply the DMSO and related therapies.    TRH