Tag Archives: dupuytren

Does Neprinol replace the Nattokinase, Fibrozym and Quercetin Bromelain Complex in the treatment of Dupuytrens?

Posted on by

Dr Herazy,

Does Neprinol replace the Nattokinase, Fibrozym and Quercetin Bromelain Complex in the treatment of Dupuytrens?

Thanks,

Mike Scully

 

Greetings Mike,

People who follow the Dupuytren Contracture Institute treatment concept use Neprinol in one of two ways – either as a total substitute for the other enzyme products, or in addition to them (usually with the Neprinol being the primary enzyme source and the others being used as a minor role).  The choice is yours.  I have long advised people to try Neprinol both way while assessing for which method brings about best change in the hand lump.

I would consider trying just the Neprinol by itself, and see how it works for you and the palm lumps.  If that is not enough to get your fibrous tissue to change favorably, then bring back the Fibrozym or Nattokinase, or Quercetin/Bromelain if you are also using it, or all of them.  A common strategy that is used is to take about 6-8 Neprinol daily, while taking 2-3 Fibrozym and 2-3 Nattokinase daily; all of these are taken between meals, as I am sure you know.  However, you also must know that Dupuytrens treatment is not just about using systemic enzymes to reduce the lumps on the palms.   You must also use other nutrients as  and treatment strategies at the same time to support the best change possible.

You must keep experimenting to learn what makes your scar respond favorably and then continue with that.   TRH

I think my wife has Dupuytren contracture, what should we do?

Posted on by

Hi Doctor,

My wife is 47 years young and has been a diabetic for 20 years.  A few months we started to notice a small kind of hard lump in her hands, that has started to grow and it appears to be stretching out underneath her skin, but still has the same lump.  There is a total of 3, she is now having some problems in her finger joints and starting to affect her closing her hand, she can still lay her hand flat, OK.  She has been to the Dr, and has had a few test.  Blood work is 100% good and it has been done already twice.  X-rays, don’t show anything, ultra sound showed that the Dr. said are fibroids, which I don’t believe that’s what it is.

By looking at images and stories on the internet I feel she has Dupuytren.  So please tell me what you think and if this is what she has.  What should be our next move?

 

Greetings,

No one can make a diagnosis on the limited information you have supplied.  Your wife should be examined again for a second opinion. 

There is one thing you mention that does not sound like your wife has Dupuytren’s contracture, and that is “starting to affect her closing her hand.”   If she had Dupuytren’s contracture she would not have a problem closing her hand, she would have a problem opening her hand.   The fact that she can still flatten her hand on a tabletop might only be because she is in she early stage of DC.

Good luck to both of you.  TRH

What do you think about my palm that split open after Xiaflex injections for Dupytren contracture?

Posted on by STL314

Two days after injection with Xiaflex for my Dupuytrens contracture, during the attempted release of the pinky and ring fingers on my right hand, the skin of the palm of my hand under those fingers split open, leaving a rather deep hole approximately 1.5″ square +/-.   I have been told it happened because of previous surgery some 40 years prior.  I have been told a skin graft might be advisable if the hole does not heal quickly on its own.

Your input would be appreciated.

 

Greetings,

Sorry to hear of the complication from Xiaflex hand surgery.   Your situation of the palm skin splitting open is not uncommon; it happens with some frequency although doctors tend not to discuss or warn patients about this complication.  I suspect this information is kept from patients so they will not refuse Xiaflex hand surgery.  

We both know I am not involved in the treatment of your hand and have no direct knowledge of your past or current condition.  I only know the very limited things about your Dupuytren surgery with Xiaflex injections you mentioned here.   Because of this limited information I can only ask questions:

1.   Was the doctor who did your Xiaflex injections aware you had prior hand surgery 40 years ago,  before he injected you with Xiaflex?

2.  Did you deliberately or intentionally hide this information about your previous hand surgery from the doctor, or did the doctor not ask you about the past hand surgery?  In other words, was the doctor aware of your hand surgery 40 years previously, or not, before the Xiaflex injection series was done?

3.   Since I assume you either told this doctor about the prior hand surgery, or hand scars were visible and there was no need to tell the doctor, did the doctor warn you ahead of time that this complication or adverse reaction might occur?  Was this possible complication mentioned to you, explained in detail, and were you allowed to give informed consent to refuse or accept hand surgery with this information from the doctor?   In other words,  did the doctor talk to you in detail about the potential for this kind of problem to occur so that you knew what you were getting into and had the chance to accept or refuse hand surgery?

4.   Did the doctor explain to you that there was a chance for the Xiaflex injection to leak out from the Dupuytren cord and migrate up to the skin of the palm, causing the skin to deteriorate and burst open?

5.   If the doctor knew, or should have known, about the potential problem of injecting your hand with Xiaflex since you had prior hand surgery, what did that doctor do differently while injecting your hand with Xiaflex to prevent this complication in your case?  

6.  Did the doctor who made the Xiaflex injection that resulted in your palm splitting open, explain to you how a surgery that was done 40 years ago was able to interfere with the Xiaflex injection procedure?  In other words, if your hand tissue was stable for 40 years, what was the underlying problem that caused the Xiaflex injection to go so terribly wrong?

7.  What is the possibility the doctor who provided your Xiaflex injections simply made a mistake – as is common and easy to do during this Xiaflex injection procedure – to cause this  tissue injury and subsequent spitting to occur?  What is the possibility the doctor who provided your Xiaflex injections is simply trying to protect himself/herself from possible litigation by blaming someone or something else for this problem?

There are many cases in which these problems arise after Xiaflex injections or other types of hand surgery.  They are usually played down because this information is not good for the Xiaflex manufacturer or the doctors who do the work in the office.   I think if patients knew of the high rate of these problems – and worse– occurring, they would far less willing to allow this procedure to be done.  In my opinion it is best to avoid Xiaflex injections if at all possible by using the Alternative Medicine procedures discussed on this website.   The body can possibly reverse the Dupuytren tissue when given the opportunity. You will only know if you try.

I suggest you do all you can to increase your ability to heal and repair the skin of your palm.  Your medical doctor will not know much about this topic.  He will not explain that he has never studied or considered this topic, he will only say it cannot be done.   I suggest you contact someone who is experienced and trained in health management like a naturopath or a medical doctor who specializes in natural medicine.   TRH

 

 

 

 

Is there a substitute for DMSO I can use to treat my hand?

Posted on by

Hello Dr. Herazy,

I am researching the therapies you are recommending. Since I am allergic to Sulfa drugs I probably do not want to use DMSO. Assuming I can tolerate the topical E and the CP Serum is there another carrier oil or gel that I could use instead of the DMSO? Maybe Jojoba oil or olive oil?

Thank you

Diane B

 

Greetings Diane,

Although it is not as good as DMSO for the purpose of driving the topical E and Super CP Serum copper peptides into the Dupuytren palm nodule and cord tissue, you can use Emu oil for this purpose.    The emu is a bird from New Zealand and Australia.  Oil from this bird has some tissue penetrating properties and can be used also.   TRH

Could Xiaflex injection for Dupuytrens cause a side effect or bad reaction in my low back?

Posted on by

Hello Dr. Herazy,

I had one Xiaflex injection for my hand on a Wednesday, and had most of the normal reactions. Swelling in hand began to subside on following Monday. I had a large bruise about 2″ wide inside same arm that went from elbow to shoulder-very dark purple, then yellow, now gone (about 1 week total). My wrist on same side also showed bruise about 3″ square area.

Worst of all, I had an extreme back issue in an area where I have degenerative disc disease (L-4). I have lived with back episodes since age 15, now age 64. I have never experienced this extreme back pain, was taken to hospital via ambulance, when pain became so strong I could not move. I did help pick up a piece of steel on Monday, nothing unusual or extreme, then I had usual sore back until Wednesday AM, when I awoke and could barely get out of bed. I had to go to the floor, then work my way onto my feet.  I could not turn, lean forward or backward or twist, lift anything.  Tried ice pack, double dose Tylenol 3 with codeine, and Biofreeze. Finally became totally immobilized due to intense pain, called 911, went to ER, several muscle relievers and pain shots, came home and am taking medication now. In my adult life, I have never experienced anything near this intense. I wonder if the Xiaflex softened/weakened the tissue between the disc in my back enough to cause this problem.

I would like to hear if other chronic back patients who suffer milder problems same as I do every six months or so had an extreme reaction. Are there others with chronic bone/nerve connectivity issues who also had extreme occurring?

It seems plausible because of the reaction up my arm that the drug also could be carried into other parts of the body, weakening tissue.

Thanks.

 

Greetings,

I have explored this topic at some length for you.  While there is some small suggestion that Xiaflex might migrate from the primary area where it is injected, the research – at this time – says that it would be stopped at the lymph nodes.  In the case of Xiaflex treatment for a Dupuytren hand problem, this would mean it would probably go no further than the lymph nodes in the armpit. There is no current report of Xiaflex traveling throughout the body, as you suggest.

It would seem that the most likely explanation is that your extreme low back pain flareup was not much more than a coincidence.    TRH