What is the concentration of DSMO in your Dupuytrens product ?

Is your DSMO medical grade? What is the concentration of DSMO  in your product ?



The DMSO product we use was created by Stanley Jacobs, MD, the medical researcher who first discovered the medical uses for DMSO in treatment of humans in the late 1950s, and is made for us by his laboratory in Washington state.   So, yes, the DMSO we use is definitely of medical grade for use in treatment of human medical conditions. 

The concentration of the DMSO in our product used to treat Dupuytren’s contracture, called Dusa Sal, is 60%, along with urea, vitamin E, methyl salicylate, natrolsol, propylene glycol and demineralized water.  Mind you, if 100% was the correct concentration of DMSO to help this problem you can assure that Dr. Jacobs could easily have done that, but this is one of those situations where more is not always better.  With this lower concentration of DMSO you will be able to use it longer and more often – and this is what gets you better results.    TRH

Is there a substitute for DMSO I can use to treat my hand?

Hello Dr. Herazy,

I am researching the therapies you are recommending. Since I am allergic to Sulfa drugs I probably do not want to use DMSO. Assuming I can tolerate the topical E and the CP Serum is there another carrier oil or gel that I could use instead of the DMSO? Maybe Jojoba oil or olive oil?

Thank you

Diane B


Greetings Diane,

Although it is not as good as DMSO for the purpose of driving the topical E and Super CP Serum copper peptides into the Dupuytren palm nodule and cord tissue, you can use Emu oil for this purpose.    The emu is a bird from New Zealand and Australia.  Oil from this bird has some tissue penetrating properties and can be used also.   TRH

Does DMSO produce an offensive odor?

DMSO – odor? A veterinarian warned me that DMSO usually produces offensive odor, is this an issue? (I am considering starting with your medium plan)


Since it seems that most people who mention the garlic odor issue related to DMSO are veterinarians, I must assume this is a problem when dealing with animals in a veterinary practice.   I have been doing this work with Dupuytren contracture since 2002 and no one has complained to me about the garlic smell being an actual problem.

Those who mention anything about it refer to a brief garlic taste in the mouth for a few minutes after applying DMSO, but it leaves as quickly as it arises.  

Those who read about this phenomenon assume it is some terrible and socially-violating issue, and from extensive experience it most definitely is not.    TRH

What do you recommend I start treatment with?

hi there,

i’ve had dupuytrens and peyronies for over ten years. i took neprinol for several months without effect, then something called vitalzym. over the last year or so i have sort of given up. now i would like to start again. i would like to start with the medium plan. but i have plenty of dmso and have already taken neprinol. what do you recommend i start with? and what would the cost be? thank you.


Thank you not only for you questions, but thank you for not giving up on yourself.   Some of the most positive results and grateful changes have happened with men who have had their DC and PD for many years and after many failed attempts.

Saying you took Neprinol for several months means nothing to me since, 1. you do not indicate exactly how you took it, and 2., we never recommend that anyone takes Neprinol by itself.  You used it incorrectly in my opinion.

Since you were using these therapies on your own without guidance it is obvious you were using them incorrectly (such as taking Neprinol by itself).   Please do not make the mistake of dismissing the value of Neprinol because you did not use it correctly.  Using Neprinol, or any other therapy that is in the DCI and PDI lineup, is not as simple as popping a few pills a day and hoping that you get over your problem.   There is a right way and a wrong way to do a lot of things in life, and DC and PD treatment with Neprinol or vitamin E or DMSO is no different.   Too bad the people who sold you the Neprinol did not know enough to give you guidance for its correct use.

You seem to have the opinion that since you experimented unsuccessfully with using Neprinol by itself in the past you assume the product is the fault for your lack of results, not how you went about using it.  If that is the case, it is my opinion you are incorrect.  Neprinol is a great product as I have written many times, but as good as it is it must be used in the right way and in combination with other therapies in a synergistic fashion for best results.

Look at it this way:  Tarred roofing shingles are a great product to put on the top of a new house.  If you built a house entirely of tarred roofing shingles it would not make for a successful house.   If you told people that tarred roofing shingles are bad because they did not create the results you desired, they might get the wrong idea.   Tarred roofing shingles are a part of a well built home.  However, they must be combined with lumber, and windows, and nails, and plaster board, and plumbing and electrical components, and hundreds of other things to make a fine home.  How you combine them determines the end result.  If your shingle house was a failure do not blame the shingles, blame the person who told you to try to do the entire job with just one product.

I can understand why a person would give up the kind of treatment you have  attempted after a while.   Many men get frustrated after a few weeks of guessing and experimenting without knowing what to do.

The DCI or PDI medium plan is a well balanced modest cost plan,  and for this reason it has been our most popular starting point.  When you receive your first order parcel you will be impressed with the amount of information that is enclosed with your order, telling you exactly what to do and what not to do to achieve the best results you can.

Saying you have plenty of DMSO means nothing to me because I have no idea of the quality of your product or the formulation. Most of the time people come to me after using a 100% DMSO product, thinking that stronger is better. That is usually the wrong thing to do for a variety of reasons.  We get good results with our PMD DMSO and Dusa Sal DMSO formulae from the laboratory of  Dr. Stanley Jacobs.   Both these products are not close to 100% DMSO and this is part of the reason they both work so well.  If you want to use your DMSO product, whatever it is and whatever it contains, that is your decision.  I cannot comment on it because I know nothing about it.

Since you ask my opinion how you should start your treatment, I will answer that you should start by getting my first book, “Peyronie’s Disease Handbook” and study it.  Do not buy any kind of treatment products until you have a better idea of how and why you are using any of these things.  This book  will put your feet on the ground with both PD and DC treatment concepts so you will know what you are doing.  Up to this point you have been guessing about treatment.  After you read the book you will know much more about what you should be doing to help yourself.   You should also spend a few hours going over the DCI and PDI websites to educate yourself how to go about using Alternative Medicine to promote and support natural healing.  It is not as easy as grabbing a therapy product here and later another therapy product there, hoping something good happens.

Let me know if you have specific questions about DC and PD treatment.  TRH

DMSO Questions

I the dmso you sell a “pharmaceutical” grade or “industrial” grade?

How is the dmso applied and in what amount?


The DMSO is  of a pharmaceutical grade from the oldest medical DMSO source in the U.S., still operated by Stanley Jacobs, MD, who did the original research at the Washington State School of Medicine on the medical use of DMSO in the late 1950s.   Dr. Jacobs is in his 90s and still teaches and works in the laboratory at the medical school.  We use his Dusa Sal formula that he recommends for Dupuytren contracture.

The Dusa Sal DMSO is applied to the hand directly over the palm nodule and cord formations, usually just a few drops per application.   In additional to the Dusa Sal we recommend that you also use vitamin E oil and a copper peptide at the same time.    When you get Dusa Sal from DCI you will receive a detailed instructional sheet of information in your order so that you know exactly how to apply the DMSO and related therapies.    TRH