How should I change my Dupuytren’s contracture treatment plan for best results?

I have been applying the recommended Dupuytrens therapy for about four months with increases to try to get to the maximum.  Currently I am taking both E vitamins internally and vitamin E, copper and DMSO externally.  I started with Neprinol a few weeks ago and currently take 2 querecitin/bromelain, 4 Neprinol, fundamental sulfur and PABA twice a day. After the DMSO treatment I stretch and massage my fingers and the palm of my hand that has some blister-like areas over the palm where I think I should be massaging but it concerns me that I may be increasing the blisters by so doing.  I hope I am proceeding correctly with the massage. I have not seen any appreciable improvement except that before the DMSO and massage I get a reading of 122 and then it has gone to 126 – 128 after the stretch and massage however it reverts to 122 by the next treatment time. I have been getting good reduction of an external scar from a previous surgery on my other hand by an aggressive stretching and massage as well as scraping (as though it was a callous) after the DMSO treatment. I am not sure if the internal and external therapies are working as they should although I think I am using a pretty aggressive plan. Hopefully I am on track.
DLB

 

Greetings DLB,

Yes, you are on the right track for your Dupuytren’s contracture treatment but I think you need to be more proactive with your plan. 

You are using your assumption for what an aggressive plan might look like, and you are counting pills to tell yourself that you are following an aggressive plan, to tell yourself that your plan is active and aggressive when in fact it is not.   Based on my experience with plans that have been developed over time that are getting results, I see that they are larger and more aggressive than what you are taking currently. 

If you have followed this plan for four months with increases as you say, then you have either started at an extremely low dosage, or you have increased your therapy intake very slowly with many weeks or even months between increases, or you have increased at a very low level of intake per increase.  Perhaps all of these are true, since you did not give information how you came to be taking this current dosage level.  This lack of information of how you have been working these increases puts me at a disadvantage to guide you to make increases going forward. 

I do not know what you mean by a blister on your palm.  When you mention blister in your email I would have to assume you know what a blister looks like and what to do about that.  If you mean a nodule or lump of denser than normal tissue that is consistent with Dupuytren’s contracture, then I can comment about that type of finding.

There is early indication of progress in that the increased temporary movement from 122 to 126/128 is not small.  A lot of people would like to have that change happen in the early part of their treatment course.   Over time, and with appropriate increase of your intake you should see these numbers increase as well as notice reduction of size, shape, density and adhesion of the nodules and cords.

Overall, your plan is rather modest in spite of it being applied for the last four months.  It seems you are being very conservative and slow in your response to the results that you are earning. I suggest that you consider increasing the Neprinol intake to 9/day, following the directions that are given to you with each order.  I cannot describe that long detailed procedure to work up to 9/day in this email response.  All you need to do is to read and follow the directions you already have that explain how to increase therapy levels safely and effectively.  I also suggest that you contact me about a phone discussion so I can get down to some of the details of how you should be stretching your contacted palm tissue.  I suspect you might be going about this incorrectly, and if so this might be an additional factor in your slow response.    TRH

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