Dupuytren’s Contracture and Cirrhosis: Chronic Liver Disease

Cirrhosis and liver disease as a cause of Dupuytren contracture

The predisposition and causation of Dupuytren contracture as a result of cirrhosis of the liver is not clear; more clearly established correlations exist:

  • People of Northern European (UK) and Scandinavian descent
  • Men rather than women; men are 10 times more likely to develop Dupuytren contracture between the ages of 40 and 60 years, after which the incidence rate increases for women later in life to become equal by 80-85 years
  • Workers who sustain constant micro-traumatic stress to the tendons of the hands (carpenters, bricklayers, rock climbers, jackhammer operators, etc.)
  • People over the age of 40; age as a factor increases as age increases
  • People with a family history (grandparents, parents, uncles, aunts, cousins)

Currently, unproven but interesting causes of Dupuytren’s hand contracture include diabetes, alcoholism, epilepsy therapy with phenythoin and liver disease.

A higher rate of Dupuytren contracture occurs in those with cirrhosis and related liver disease caused by alcohol abuse, as compared with those with cirrhosis and liver disease not associated with alcohol consumption.  It is important to note it is not alcohol consumption, per se, that appears to be a contributory factor for Dupuytren contracture but the abuse of alcohol intake, especially over an extended time.  Further, to keep contributory factors in perspective and rightfully appreciated, it is important to note that age and genetic predisposition to Dupuytren’s disease, as revealed by family history, are of greater contributory importance than alcohol abuse and resultant liver cirrhosis.

Dupuytren contracture and cirrhosis, liver disease and alcoholism

Perusal of recent studies that investigate the correlation of Dupuytren contracture and cirrhosis, liver disease and alcoholism reveals variable results and inconsistent conclusions.   The general trend of findings points toward the higher prevalence of Dupuytren contracture in chronic alcoholics and absence of correlation between Dupuytren contracture and chronic liver disease.  Alcoholics tend to have a higher rate of Dupuytren’s disease, and this is thought to primarily due liver disease caused by alcohol abuse.  Age, male incidence and genetic factors are of greater causation and predisposing factors than cirrhosis and liver disease.

If you male, and over 50 years of age, with a history of Dupuytren contracture in your family and heavy alcohol consumption, it would be wise to do all you can to reduce your chance of cirrhosis and liver disease.  You cannot do much about your gender, age and family genetics, but you can eliminate liver disease risk factors that might favor development of Dupuytren contracture.

Once Dupuytren contracture is present and someone learns that there is no known medical treatment available other than risky surgery, consider using Alternative Medicine as a Dupuytren contracture treatment option.  This is an option that the Dupuytren Contracture Institute has researched and developed since 2002, with considerable treatment success. To learn more, click Dupuytren treatment success.

Comments

2 Responses to “Dupuytren’s Contracture and Cirrhosis: Chronic Liver Disease”
  1. Alison says:

    Above, we read about the causation of Dupuytren’s contracture:

    1. “The general trend of findings points toward the higher prevalence of Dupuytren contracture in chronic alcoholics and absence of correlation between Dupuytren contracture and chronic liver disease.”

    2. “Alcoholics tend to have a higher rate of Dupuytren’s disease, and this is thought to primarily due liver disease caused by alcohol abuse.”

    These two statements appear to contradict one another. It there, or is there not, a correlation with liver disease caused by alcohol as it relates to Dupuytren’s contracture?

  2. Dr.Herazy says:

    Greetings,

    Welcome to the world of Dupuytren’s contracture: conflicting opinions and few hard facts.

    You are expecting to find a definitive and standardized set of facts regarding Dupuytren’s contracture, and there are only a few. Causation of Dupuytren’s contracture is still unsettled, but likely of multiple potential etiology; the one that gets little attention is chronic upper extremity tension that reduces full blood and lymphatic circulation. From my experience the causation of liver disease is unimportant, whether of alcohol, age, infirmity or drug etiology. At this time the best that can be said is that there a strong, but undetermined, correlation between liver disease and alcoholism and Dupuytren’s contracture. TRH

Speak Your Mind

Tell us what you're thinking...
and oh, if you want a pic to show with your comment, go get a gravatar!